Biacore sensor chip for orientation-specific binding of antibodies (predominantly human) through Fc-region.
With MabSelect SuRe ligand on the surface.
Site-directed capture of antibody: binds only to the heavy chain within the Fc region and ensures antibodies are bound to the surface in a specific orientation.
Time and effort savings: ready-to-use sensor chip eliminates the need to develop immobilization and regeneration conditions.
Confidence in data: highly controlled development processes and manufacturing conditions ensure reproducible results.
Surface description
Carboxymethylated dextran matrix with a recombinant Protein A variant covalently attached. The surface ligand is the same as is used for our MabSelect SuRe protein purification products.
Binds antibodies from several mammalian species, most notably human antibodies of the subclasses IgG1, IgG2, and IgG4.
Binds only to the heavy chain within the Fc region, ensuring a specific orientation of the antibody on the surface.
Does not bind Fab fragments (unlike native Protein A).