4titude¢ç's Clear Weld Heat Seal Mark 2 (4ti-0575) heat sealing film is available pre-mounted to create a FrameSeal¢â. Together with the Fraunhoffer IPA Institute, FrameSeal¢â has been used in a fully integrated solution for sealing 1536 well PCR plates before analysis of RNAi screening with a Roche LightCycler¢ç 1536, as shown below.
Using a robotic arm, a single FrameSeal¢â is placed onto a 1536 well PCR plate. By adjusting the position of the robot gripper, the plate and FrameSeal¢â combination are then transferred to the drawer of a 4s3¢â Semi-Automatic Sheet Heat Sealer, which seals the part via a software command through its RS232 port.
After the sealing process has been carried out, the sealed plate is transferred to the De-Framer, which separates the frame from the film at each point along the edge of the film. The frame can then be removed, leaving the sealed plate to be placed in the cycler.
Together, the heat sealer and the FrameSeal¢â are:
- The most cost effective automated heat sealing solution available
- A solution to the demand from diagnostics customers for sterile, single-use consumables
- The most compact instrument for easy integration
For more information on how this automation cell was set up, please click here.